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Showing 25 of 809 items meeting your criteria.
| Type | Category | Supplier | ||
|---|---|---|---|---|
 | KACTUS has developed a catalogue of full-length multipass transmembrane proteins displayed on virus-like particles (VLPs) or copolymer nanodiscs for immunisation, affinity testing, PK/PD studies, antibody characterisation and other drug discovery applications. | |||
Documents | Proteins | KactusBio Inc. | ||
 | Neuromics is proud to introduce their newest pioneering research tools - human Cas9 expressing primary cells and GPCR expressing cell lines. With these modifications, the cells are valuable and versatile options for drug discovery, studying disease mechanisms, and countless other applications. | |||
Documents | Primary Cells | Neuromics | ||
 | Abnovas VHH nanoBiTE™ service focuses on developing bispecific VHH antibodies without an Fc domain, ideal for immune and tumor cell redirecting, multiple epitope targeting, and novel immuno-oncology research. Their smaller molecular size enhances tissue penetration, making them suitable for hard-to-access areas like the tumor microenvironment. The absence of an Fc region prevents unwanted immune activation by avoiding Fc receptor binding, supporting precise mechanistic action. Engineered through the genetic fusion of two VHH domains via a flexible peptide linker, VHH nanoBiTE™ ensures robust antigen binding with reduced production complexity. | |||
Documents | Service | Abnova Corporation | ||
 | Leadgene Indoxyl Sulfate (IS) ELISA Kit is a competitive enzyme-linked immunosorbent assay (competitive ELISA) for quantitative detecting total indoxyl sulfate (IS) levels in human serum samples. It is used as an aid in the diagnosis of renal function. However, it is intended for in vitro diagnostic use only, NOT suitable for use in therapeutic procedures. | |||
Documents | Datasheets | LeadGene Biomedical | ||
 | GMP-Grade & Research-Grade Enzymes for Gene Editing | |||
Documents | Enzymes | KactusBio Inc. | ||
 | KACTUS provides a range of GMP-grade and research-grade IVT enzymes for large-scale mRNA production. | |||
Documents | Enzymes | KactusBio Inc. | ||
 | KACTUS excels in crafting and producing an array of superior-grade, highly active recombinant proteins and enzymes, catering to diverse sectors like antibody drug discovery, immunotherapy, biologics and cell therapy. Their expansive catalog, boasting over 3000 recombinant proteins, encompasses a wide spectrum of targets, species, tags, and labels, each thoughtfully chosen to address the specific, unmet needs of scientists engaged in drug development. The hallmark of their product selection process is a rigorous emphasis on exceptional quality and a steadfast commitment to ensuring reliable supply, thereby upholding the highest standards of excellence and client satisfaction. | |||
Documents | Catalogue | KactusBio Inc. | ||
 | In vitro transcription (IVT) utilizing T7 RNA polymerase (T7 RNAP) for the synthesis of messenger RNA (mRNA) is efficient and well-established for the production of large quantities of synthetic RNA. However, T7 RNAP can generate undesirable, immunostimulatory mRNA byproducts such as double-stranded RNA (dsRNA). To reduce these concerns, we rationally engineered a series of T7 RNAP mutants and compared their functional properties to those of wild-type and commercially available T7 RNAP. Among these characteristics are dsRNA, circular RNA, processivity, and yield. | |||
Documents | RNA | KactusBio Inc. | ||
 | When dealing with solid tumors lacking specific biomarkers, the effectiveness of adoptive T cell therapy using TCR-T treatments is limited. We believe that the absence of dependable, multifaceted MHC reagents has been a hindrance in the research and development of treatments for solid tumors. To address this unmet need, we have engineered MHC molecules in several formats with diverse applications and high stability. These improved, highly active MHC molecules have the potential to facilitate solid tumor research and development. | |||
Documents | Cancer | KactusBio Inc. | ||
 | G protein-coupled receptors (GPCRs), also known as seven-transmembrane receptors, represent the most important class of drug targets. However, extraction and purification of membrane proteins like GPCRs, ion channels, and transporters are generally challenging due to low expression levels and the hydrophobic nature of transmembrane segments. To tackle this challenge, we have engineered and produced GPCRs in VLP and/or nanodisc formats, which have been successfully applied to GPCR antibody drug discovery and various in vitro assays. | |||
Documents | Drug Discovery | KactusBio Inc. | ||
 | Case study demonstrating the application of peptide-ready MHCs in identifying antigen-specific T cells. A leading TCR company used peptide-ready MHCs to identify antigen-specific CD3+ cells using their own proprietary peptide and TCR-expressing cell lines. KACTUS peptide-ready MHCs were able to distinguish complete TCR expressing cell populations from incomplete TCR expressing cell populations. | |||
Documents | Tetramers | KactusBio Inc. | ||
 | KACTUS offers experienced SPR assay services with various sample combinations and detection methods to meet the unique needs of your binding and affinity experiments. | |||
Documents | Service | KactusBio Inc. | ||
 | Unleash the Power of B Cell Expansion for Clinical Research & Immunotherapies | |||
Documents | Cell Biology | AdipoGen Life Sciences | ||
 | Unleash the Power of B Cell Expansion for Clinical Research & Immunotherapies | |||
Documents | Cell Biology | AdipoGen Life Sciences | ||
 | Peptide-based Tools for Obesity & Diabetes Research | |||
Documents | Metabolism | AdipoGen Life Sciences | ||
 | Adipogen Life Sciences provides products for B & T Cell Expansion - B-Xpander and InVivoKines. | |||
Documents | Cell & Gene Therapy | AdipoGen Life Sciences | ||
 | KACTUS offers custom full-length solute carrier protein expression services displayed on VLPs or nanodiscs for various drug discovery applications. | |||
Documents | Proteins | KactusBio Inc. | ||
 | Catalogue and custom services for MHC Monomers, Tetramers, and Soluble TCRs to meet various needs in immunotherapy research. KACTUS team has extensive experience in MHC and TCR engineering and expression and performs quality testing for bioactivity. | |||
Documents | Tetramers | KactusBio Inc. | ||
 | KACTUS has successfully developed a high-quality recombinant Laminin 521 that can be applied to scientific research (research-grade) and preclinical development (preclinical-grade). | |||
Documents | Recombinant Proteins | KactusBio Inc. | ||
 | Cell culture is the cornerstone for advancements in cell therapy and organoid development. KACTUS has crafted an array of premium cytokines tailored for the cultivation of cells and organoids, creating a reliable foundation for research in these areas. | |||
Documents | Cytokines | KactusBio Inc. | ||
 | Expertly Designing & Manufacturing Recombinant Proteins & Enzymes | |||
Documents | Supplier Introduction | KactusBio Inc. | ||
 | Claudin 18.2, a small transmembrane protein with 4 transmembrane domains and two extracellular loops, is overexpressed in a significant proportion of gastric cancers and oesophagal adenocarcinomas. In 2018, KACTUS was the first company globally to express full-length wild-type Claudin 18.2. | |||
Documents | Proteins | KactusBio Inc. | ||
 | AccuBase™ is a cytosine base editor engineered by Base Therapeutics and manufactured for global sales by KACTUS. It creatively embeds a deaminase inside the Cas protein to prevent random binding of deaminase to non-target sites, significantly reducing off-target occurrence while still maintaining high editing efficiency. | |||
Documents | Enzymes | KactusBio Inc. | ||
 | Detect full and empty AAV capsids specific to AAV2, AAV5, AAV6, AAV8, or AAV9 serotypes via ELISA. | |||
Documents | ELISA | KactusBio Inc. | ||
 | KACTUS provides enzymes for in vitro DNA amplification and modification. | |||
Documents | Enzymes | KactusBio Inc. | ||