Welcome to ProSci - Distributed in the UK & Ireland by Caltag Medsystems
ProSci
ProSci a broad catalogue of over 30,000 research antibodies and has completed over 20,000 Custom Antibody projects.
Their in-house labs and animal facilities (USDA licensed and NIH/OLAW approved) provide an extensive array of antibody products & services, with a focus on providing the highest quality monoclonal, polyclonal, and single domain antibodies.
ProSci's expertise in antibody production, immunochemistry services, and biological research is realised through customisable services, innovative products, competitive pricing, high-quality research tools, and unparalleled technical support.
Established in 1998, ProSci is a reliable partner with over 20 years of serving the research community globally.
Antibodies
ProSci specialises in the production of affinity-purified peptide-specific antibodies to novel antigens in fields such as HIV, Apoptosis, Signal Transduction, Neurobiology, Autophagy, and Immunology.
Affinity-purification allows for the isolation of antibodies specific to the epitope of interest. This results in ProSci's polyclonal antibodies having the same specificity as monoclonal antibodies at a competitive price.
Single Domain Antibodies
ProSci's Single Domain Antibody products are highly valuable in fundamental research, diagnostic, and therapeutic applications.
Single Domain Antibodies (sdAbs), also known as VHH antibodies or nanobodies, are isolated from camelid heavy chain only antibodies and are comprised of only the variable domain. As such, they lack light chains, are smaller and more stable compared to conventional antibodies, yet possess fully functional antigen-binding capability.
Due to their size (approximately 15 kDa) and their longer CDR3 region, a single domain antibody is adept at reaching otherwise inaccessible epitopes that may play a crucial role in the molecular mechanisms of disease.
Single Domain Antibodies - Podcast
Single Domain Antibodies - Video
Research Grade Biosimilars
Beyond therapeutics, monoclonal antibodies (mAbs) shown to be effective in the clinic can help to facilitate laboratory research.
mAbs, also known as biosimilars, are useful tools to research novel therapies and uncover effective off-target applications.
With known and approved data on toxicity and efficacy, these biologics are used as benchmarks to accelerate findings from bench to clinic.
ProSci has more than 800 research-grade biosimilar antibodies available in the following research areas:
Recombinant Proteins & Peptides
ProSci's recombinant proteins are available as monomers, dimers, trimers, and multimers.
Full-length and partial-length proteins are available for control experiments, assay development, and antibody development projects.
Utilisation of E. coli, mammalian, yeast, and baculovirus expression systems with various activity assays have been performed to ensure functionality.
Applications of ProSci's recombinant proteins include CLIA, EIA, IM, Lateral Flow, and WB.
As well as recombinant proteins, ProSci also provides peptides. Match one of ProSci's peptides with a primary antibody for blocking and control experiments.
Research Areas
Immunology
Uncover highly validated tools to decode immunological pathways for fighting diseases. ProSci's catalogue has over 500 antibodies, biosimilars, and antibody pairs.
Cancer
ProSci has a vast offering of antibodies to support cancer research.
Neuroscience
With many reagents dedicated to neuroscience research, ProSci continues to support scientists worldwide with the best tools to excel in their research.
Immune Checkpoints
ProSci has developed several classes of reagents that can be used to study the actions of multiple immune checkpoint proteins such as CTLA-4, PD-1, and its ligands, PD-L1 and PD-L2.
Viral Infectious Diseases
Recent viral epidemics and pandemics have devastated lives and populations on a global scale. To support biomedical viral research and epidemiological studies in these devastating diseases, ProSci offers research reagents for the study of many known viral disease agents including Coronaviruses, HIV, and Influenza.
ProSci also provides products for the following research areas:
Other Products
ProSci also offers a complete assortment of cell & tissue lysates, antibiotics & antimicrobials, isotype controls, and more to complement the use of their antibodies, peptides, and recombinant proteins.
ProSci Custom Antibody Services
High-quality technical assistance, competitive pricing, and highly customisable projects qualify ProSci staff as experts in custom antibody development & production.
The value and convenience of ProSci's custom antibody production services are further advanced with a complete spectrum of available immunochemistry services. These include (but are not limited to) antigen design assistance, peptide synthesis, protein conjugation, and immunisation.
Caltag Medsystems is here with you every step of the way to support your custom antibody project with ProSci.
ProSci custom antibody services include:
ProSci Support
For further ProSci information, please visit prosci-inc.com.
To find informative antibody protocols, downloadable content, and other reference materials, please visit Application & Techniques.