The MHC Monomer is a sub-component of an MHC Tetramer, made up of the MHC complex (α-chain plus β-2 microglobulin for class I or α-chain plus β-chain for class II) folded together with a specific peptide. Biotinylated Monomers are available for most associated Tetramer products.
Investigators often select MHC monomers to create tetramers in their own labs with alternate labels or to generate smaller tetramer batches. Alternatively, others use monomers for screening or immunisation strategies.
MBLI’s Biotinylated MHC monomers, Class I or Class II are now available for tetramer construction flexibility and novel applications. For example, the production of metal-labelled tetramers for use with CyTOF instruments using MBLI monomers.
Information provided by MBL.
Caltag Medsystems is the distributor of MBL products in the UK and Ireland. If you have any questions about these products, please contact us.