ProSci

CD94 Antibody [18d3] (Biotin)

Product Code:
 
PSI-98-972
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[18d3]
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Blocking
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
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PSI-98-972-0.5mg0.5mg£597.00
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Further Information

Additional Names:
Kp43, KLRD1
Application Note:
CD94 Antibody [18d3] for use in flow cytometry assays.
Background:
The monoclonal antibody 18d3 reacts with the mouse CD94 receptor subunit, a type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells, and some memory phenotype CD8+ cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
Biotin
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CHO cells transfected with the B6 allele of CD94
NCBI Gene ID #:
16643
NCBI Official Name:
killer cell lectin-like receptor, subfamily D, member 1
NCBI Official Symbol:
Klrd1
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
O54707
Research Area:
Immunology
SPECIFICITY:
CD94
Swissprot #:
O54707
User NOte:
Optimal dilutions for each application to be determined by the researcher.