ProSci

H-2Dd Antibody [34-5-8S]

Product Code:
 
PSI-99-080
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[34-5-8S]
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Immunohistochemistry- Frozen Section (IHC-F)
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-99-080-0.5mg0.5mg£560.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
MHC Class I
Application Note:
H-2Dd Antibody [34-5-8S] for use in flow cytometry, immunocytochemistry, immunoprecipitation, ELISA, CMCD, blocking, purification, and adhesion assays.
Background:
The monoclonal antibody 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of alpha1 and alpha2 chains when complexed with beta2-microglobulin. The antibody does not react with H-2Dd alpha chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
BDF1 mouse splenocytes
NCBI Gene ID #:
14964
NCBI Official Name:
histocompatibility 2, D region locus 1
NCBI Official Symbol:
H2-D1
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P01899
Research Area:
Cancer,Obesity,Signal Transduction
SPECIFICITY:
H-2Dd
Swissprot #:
P01899
User NOte:
Optimal dilutions for each application to be determined by the researcher.