Further Information
platelet adhesion molecule, platelet F11 receptor, junctional adhesion molecule A, junctional adhesion molecule 1, OTTHUMP00000027881, OTTHUMP00000027880, PAM-1, KAT, JCAM, JAMA, JAM1, JAM-A, JAM-1, JAM, CD321, F11 receptor, F11R, UNQ264/PRO301
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 30-238 of human F11R (NP_058642.1).
50848
F11 receptor
F11R
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 40kDa
Affinity purification
Cell Cycle, Immunology, Signal Transduction
Q9Y624
Optimal dilutions for each application to be determined by the researcher.