Antibody Clonality:
Polyclonal
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
1 / 5
![Western blot analysis of extracts of various cell lines, using PPP1CA antibody (14-440) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit. Western blot analysis of extracts of various cell lines, using PPP1CA antibody (14-440) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.](https://www.prosci-inc.com/static-images/14-440_1.jpg)
2 / 5
![Immunohistochemistry of paraffin-embedded human liver cancer using PPP1CA antibody (14-440) at dilution of 1:100 (40x lens). Immunohistochemistry of paraffin-embedded human liver cancer using PPP1CA antibody (14-440) at dilution of 1:100 (40x lens).](https://www.prosci-inc.com/static-images/14-440_2.jpg)
3 / 5
![Immunohistochemistry of paraffin-embedded human esophagus using PPP1CA antibody (14-440) at dilution of 1:100 (40x lens). Immunohistochemistry of paraffin-embedded human esophagus using PPP1CA antibody (14-440) at dilution of 1:100 (40x lens).](https://www.prosci-inc.com/static-images/14-440_3.jpg)
4 / 5
![Immunohistochemistry of paraffin-embedded human esophageal cancer using PPP1CA antibody (14-440) at dilution of 1:100 (40x lens). Immunohistochemistry of paraffin-embedded human esophageal cancer using PPP1CA antibody (14-440) at dilution of 1:100 (40x lens).](https://www.prosci-inc.com/static-images/14-440_4.jpg)
5 / 5
![Immunohistochemistry of paraffin-embedded mouse brain using PPP1CA antibody (14-440) at dilution of 1:100 (40x lens). Immunohistochemistry of paraffin-embedded mouse brain using PPP1CA antibody (14-440) at dilution of 1:100 (40x lens).](https://www.prosci-inc.com/static-images/14-440_5.jpg)
❮❯No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
United States.
Typical lead time:
14-21 working days.
Contact us for more accurate information.
- Further Information
- Documents
- Show All
Further Information
PPP1CA, MGC15877, MGC1674, PP-1A, PPP1A, PP1A, PP1alpha
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human PPP1CA (NP_002699.1).
5499
protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CA
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 38kDa
Affinity purification
Cancer, Neuroscience, Signal Transduction
P62136
Optimal dilutions for each application to be determined by the researcher.