Antibody Clonality:
Polyclonal
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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This product comes from:
United States.
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Further Information
IGF1R, CD221 antigen, CD221, IGF1 Receptor, IGFR, IGF-I receptor, Soluble IGF1R variant 1, Soluble IGF1R variant 2, Type 1 IGF receptor, IGFIR, JTK13
WB: 1:500 - 1:1000
IHC: 1:50 - 1:100
IF: 1:50 - 1:200
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
A synthetic peptide of human IGF1R
3480
insulin-like growth factor 1 receptor
IGF1R
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 100kDa
Affinity purification
Apoptosis, Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction
P08069
Optimal dilutions for each application to be determined by the researcher.