Further Information
CD118, LIF-R, SJS2, STWS, SWS, leukemia inhibitory factor receptor, CD118 antigen, LIF receptor, LIF receptor alpha, leukemia inhibitory factor receptor alpha
WB: 1:500 - 1:2000
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human LIFR (NP_002301.1).
3977
LIF receptor subunit alpha
LIFR
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 190kDa
Affinity purification
Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell
P42702
Optimal dilutions for each application to be determined by the researcher.
