Further Information
ATD3, DHC1b, DHC2, DNCH2, DYH1B, SRPS2B, SRTD3, hdhc11, cytoplasmic dynein 2 heavy chain 1, dynein cytoplasmic heavy chain 2, dynein heavy chain 11, dynein heavy chain, isotype 1B, dynein, cytoplasmic, heavy polypeptide 2
WB: 1:500 - 1:2000
This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DYNC2H1 (NP_001073932.1).
79659
dynein cytoplasmic 2 heavy chain 1
DYNC2H1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 492kDa
Affinity purification
Cell Cycle, Signal Transduction
Q8NCM8
Optimal dilutions for each application to be determined by the researcher.