Further Information
superoxide dismutase [Mn], mitochondrial, manganese-containing superoxide dismutase, indophenoloxidase B, Mn superoxide dismutase, MVCD6, MNSOD, IPOB, RP1-56L9.2, superoxide dismutase 2, SOD2
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:10 - 1:100
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2).
6648
superoxide dismutase 2, mitochondrial
SOD2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 23kDa
Affinity purification
Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction
P04179
Optimal dilutions for each application to be determined by the researcher.