Further Information
LCP1, CP64, DKFZp781A23186, FLJ25423, FLJ26114, FLJ39956, L-PLASTIN, LC64P, PLS2, LPL, HEL-S-37
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 368-627 of human LCP1 (NP_002289.2).
3936
lymphocyte cytosolic protein 1 (L-plastin)
LCP1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 70kDa
Affinity purification
Cancer, Cell Cycle, Immunology, Signal Transduction
P13796
Optimal dilutions for each application to be determined by the researcher.