Further Information
PSMA4, PSC9, proteasome subun, proteasome component C9, proteasome alpha 4 subunit, proteasome (prosome, macropain) subunit, alpha type, 4, multicatalytic endopeptidase complex subunit C9, MGC24813, MGC12467, MGC111191, macropain subunit C9, HsT17706, HC9
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human PSMA4 (NP_001096137.1).
5685
proteasome (prosome, macropain) subunit, alpha type, 4
PSMA4
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 29kDa
Affinity purification
Cell Cycle
P25789
Optimal dilutions for each application to be determined by the researcher.