Further Information
TPM3, FLJ41118, MGC14582, MGC3261, MGC72094, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TPMsk3, TRK, hscp30, TM5, CFTD, CAPM1, HEL-189, HEL-S-82p
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-284 of human TPM3 (NP_689476.2).
7170
tropomyosin 3
TPM3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 37kDa
Affinity purification
Cell Cycle, Signal Transduction
P06753
Optimal dilutions for each application to be determined by the researcher.