Further Information
CYP17A1, cytochrome P450, family 17, subfamily A, polypeptide 1, HGNC:2593, CPT7, CYP17, P450C17, S17AH, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia, cytochrome p450 XVIIA1, steroid 17-alpha-hydroxylase/17, 20 lyase, steroid 17-alpha-monooxygenase
WB: 1:500 - 1:2000
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 209-508 of human CYP17A1 (NP_000093.1).
1586
cytochrome P450, family 17, subfamily A, polypeptide 1
CYP17A1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 57kDa
Affinity purification
Cancer, Cell Cycle, Growth Factors, Signal Transduction
P05093
Optimal dilutions for each application to be determined by the researcher.