Further Information
APPL1, APPL, adaptor protein containing pH domain, PTB domain and leucine zipper motif, PTB domain and leucine zipper motif 1, DIP13alpha, APPL1, signaling adaptor protein DIP13alpha, AKT2 interactor, adaptor protein, phosphotyrosine interaction, PH domai
WB: 1:500 - 1:2000
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human APPL1 (NP_036228.1).
26060
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
APPL1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 95kDa
Affinity purification
Apoptosis, Cell Cycle, Neuroscience, Signal Transduction
Q9UKG1
Optimal dilutions for each application to be determined by the researcher.