Further Information
NKX2-5, NK2 transcription factor related, locus 5 (Drosophila), CHNG5, CSX, CSX1, NKX2.5, NKX2E, NKX4-1, NK2 transcription factor homolog E, locus 5, cardiac-specific homeo box, tinman paralog, VSD3, HLHS2
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human NKX2-5 (NP_004378.1).
1482
NK2 homeobox 5
NKX2-5
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 37kDa
Affinity purification
Cell Cycle, Neuroscience, Stem Cell, Transcription
P52952
Optimal dilutions for each application to be determined by the researcher.