Further Information
IL2RB, CD122, CD122 antigen, IL-2 receptor subunit beta, IL15RB, Interleukin 15 receptor, beta, p70-75, IL-2R subunit beta, IL-2RB, Interleukin 2 receptor, beta
WB: 1:500 - 1:2000
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 27-240 of human IL2RB (NP_000869.1).
3560
interleukin 2 receptor, beta
IL2RB
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 71kDa
Affinity purification
Apoptosis, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction, Stem Cell
P14784
Optimal dilutions for each application to be determined by the researcher.