ProSci

C8orf4 Antibody

Product Code:
 
PSI-22-076
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or RT
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded rat lung using C8orf4 antibody (22-076) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human stomach using C8orf4 antibody (22-076) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse lung using C8orf4 antibody (22-076) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat lung using C8orf4 antibody (22-076) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using C8orf4 antibody (22-076) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using C8orf4 antibody (22-076) at dilution of 1:100 (40x lens).

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PSI-22-076-100uL100 uL£565.00
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Further Information

Additional Names:
C8orf4, TC-1, TC1, transcriptional and immune response regulator, human thyroid cancer 1, protein C8orf4, thyroid cancer protein 1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human C8orf4 (NP_064515.1).
NCBI Gene ID #:
56892
NCBI Official Name:
transcriptional and immune response regulator
NCBI Official Symbol:
C8orf4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Apoptosis, Cancer, Cell Cycle, Signal Transduction, Stem Cell
Swissprot #:
Q9NR00
User NOte:
Optimal dilutions for each application to be determined by the researcher.