ProSci

Rhesus Macaque ACE-2 Recombinant Protein

Product Code:
 
PSI-92-726
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
blue ice or RT
Storage:
 
Store below -20˚C, stable for 6 months after receipt.
 

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PSI-92-726-0.05mg0.05mg£729.00
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Further Information

Additional Names:
Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don??™t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Buffer:
Supplied as a 0.2 um filtered solution of PBS, pH 7.4.
Fusion Tag:
C-Fc tag
NCBI Gene ID #:
712790
NCBI Official Name:
Angiotensin-converting enzyme 2
NCBI Official Symbol:
Ace2
NCBI Organism:
Macaca mulatta
Physical State:
Liquid
Predicted Molecular Weight:
110.6kDa
Protein Accession #:
ACI04564.1
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Mammalian Cells
Swissprot #:
ACI04564.1

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