anti-RhoA/B (ADP-ribosylated) (human) mAb (rec.) (VIF140-A1)
Product Code:
AG-27B-6313
Antibody Isotype:
Human IgG1
Antibody Clonality:
Recombinant Antibody
Antibody Clone:
VIF140-A1
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunocytochemistry (ICC)
- Western Blot (WB)
Storage:
Short Term: +4°C Long Term: -20°C
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This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
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Further Information
Alternate Names/Synonyms:
Ras Homologous
1 mg/ml
32160000
liquid
Liquid. In PBS.
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Please handle under sterile conditions to avoid contamination.
Recombinant ADP-ribosylated human RhoA.
Recombinant Antibody. Recognizes ADP-ribosylated human RhoA and RhoB, but not RhoC. Does not recognize unmodified non-ADP-ribosylated RhoA or glycosylated RhoA. Applications: ELISA, ICC, WB. Clone: VIF140-A1. Isotype: Human IgG1. Formulation: Liquid. In PBS. The Ras homologous (Rho) protein family of GTPases (RhoA, RhoB and RhoC) are the members of the Ras superfamily and regulate cellular processes such as cell migration, proliferation, polarization, adhesion, gene transcription and cytoskeletal structure. Rho GTPases function as molecular switches that cycle between GTP-bound (active state) and GDP-bound (inactive state) forms.
P61586, P62745
This is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
Vial
The Ras homologous (Rho) protein family of GTPases (RhoA, RhoB and RhoC) are the members of the Ras superfamily and regulate cellular processes such as cell migration, proliferation, polarization, adhesion, gene transcription and cytoskeletal structure. Rho GTPases function as molecular switches that cycle between GTP-bound (active state) and GDP-bound (inactive state) forms.
>95% (SDS-PAGE)
Protein A purified from HEK293 cell culture supernatant.
Recognizes ADP-ribosylated human RhoA and RhoB, but not RhoC. Does not recognize unmodified non-ADP-ribosylated RhoA or glycosylated RhoA.
Non-hazardous
Primary Antibodies
12352203
Stable for at least 1 year after receipt when stored at -20°C.Stable for at least 1 week when stored at +4°C.
