ProSci

TSLP Recombinant Protein

Product Code:
 
PSI-11-234
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Cynomolgus Monkey
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-234-0.1mg0.1mg£729.00
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Further Information

Additional Names:
TSLP
Application Note:
This protein carries a polyhistidine tag at the C-terminus. This protein contains a furin convertase cleavage site, 127-RRKR-130, and will be processed into N and C-terminal fragment with calculated MW of 11.7 kDa and 5.4 kDa respectively. The protein mig
Background:
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.
Background References:
  • Segawa R., et al., 2017, J. Dermatol. Sci. S0923-1811:31012-31015.
  • Wang J., et al., 2008, Cell. Mol. Immunol. 5:99-106.
  • Soumelis V., et al., 2002, Nat. Immunol. 3:673-680.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
102119254
NCBI Official Name:
thymicstromallymphopoietin
NCBI Official Symbol:
TSLP
NCBI Organism:
Macaca fascicularis
Physical State:
Lyophilized
Predicted Molecular Weight:
11.7?kDa?and?5.4?kDa
Protein Accession #:
XP_005557555.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells

Documents