EGF R Recombinant Protein

Product Code:

PSI-11-547

Product Group:

Recombinant Proteins

Supplier:

ProSci

Host Type:

Human

Regulatory Status:

RUO

Target Species:

Human

Applications:

Enzyme-Linked Immunosorbent Assay (ELISA)
Western Blot (WB)

Shipping:

blue ice or RT

Storage:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

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Code	Size	Price

PSI-11-547-0.1mg

0.1mg

£524.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Additional Names:

EGFR,ERBB,ERBB1,HER1,PIG61,mENA

Application Note:

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 94.7 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Background:

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

Background References:

Herbst RS., 2004, Int. J. Radiat. Oncol. Biol. Phys. 59 (2 Suppl): 21?6.
Giaccone, G., 2005, Ann. Onc. 16: 538-548.

Buffer:

PBS, pH7.4

Fusion Tag:

Fc Tag

NCBI Gene ID #:

1956

NCBI Official Name:

epidermal growth factor receptor

NCBI Official Symbol:

EGFR

NCBI Organism:

Homo sapiens

Physical State:

Lyophilized

Predicted Molecular Weight:

94.7 kDa

Protein Accession #:

NP_005219

Purity:

>95% as determined by SDS-PAGE.

Recombinant Protein Sequence:

#N/A

Source:

HEK293 cells

Swissprot #:

P00533

Documents

Datasheet