NSJ Bioreagents

tPA Antibody / Tissue Plasminogen Activator

Product Code:
 
NSJ-F49859
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Aliquot the tPA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
1 / 3
Western blot analysis of tPA antibody and A2058 lysate.
2 / 3
tPA antibody IHC analysis in formalin fixed and paraffin embedded human testis tissue.
3 / 3
tPA antibody flow cytometric analysis of A2058 cells (green) compared to a <a href=../search_result.php?search_txt=n1001>negative control</a> (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
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Western blot analysis of tPA antibody and A2058 lysate.
tPA antibody IHC analysis in formalin fixed and paraffin embedded human testis tissue.
tPA antibody flow cytometric analysis of A2058 cells (green) compared to a <a href=../search_result.php?search_txt=n1001>negative control</a> (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.

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CodeSizePrice
NSJ-F49859-0.08ML0.08 ml£260.00
Quantity:
NSJ-F49859-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
Application Note:
Titration of the tPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 371-399 from the human protein was used as the immunogen for this tPA antibody.
Limitation:
This tPA antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P00750