NSJ Bioreagents

Inhibin beta B chain Antibody / INHBB

Product Code:
 
NSJ-F54580
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Aliquot the Inhibin beta B chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
1 / 4
Western blot testing of human 1) A549 and 2) SK-BR-3 cell lysate with Inhibin beta B chain antibody. Expected molecular weight: 17 kDa (mature form), 42 kDa (pro peptide form) and 55 kDa (pro form).
2 / 4
Western blot testing of 1) human A549, 2) human PC-3 and 3) mouse testis lysate with Inhibin beta B chain antibody. Expected molecular weight: 17 kDa (mature form), 42 kDa (pro peptide form) and 55 kDa (pro form).
3 / 4
Western blot testing of mouse uterus lysate with Inhibin beta B chain antibody. Expected molecular weight: 17 kDa (mature form), 42 kDa (pro peptide form) and 55 kDa (pro form).
4 / 4
IHC testing of FFPE human uterus tissue with Inhibin beta B chain antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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Western blot testing of human 1) A549 and 2) SK-BR-3 cell lysate with Inhibin beta B chain antibody. Expected molecular weight: 17 kDa (mature form), 42 kDa (pro peptide form) and 55 kDa (pro form).
Western blot testing of 1) human A549, 2) human PC-3 and 3) mouse testis lysate with Inhibin beta B chain antibody. Expected molecular weight: 17 kDa (mature form), 42 kDa (pro peptide form) and 55 kDa (pro form).
Western blot testing of mouse uterus lysate with Inhibin beta B chain antibody. Expected molecular weight: 17 kDa (mature form), 42 kDa (pro peptide form) and 55 kDa (pro form).
IHC testing of FFPE human uterus tissue with Inhibin beta B chain antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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CodeSizePrice
NSJ-F54580-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54580-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Immunohistochemistry (FFPE): 1:25, Western blot: 1:500-1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the Inhibin beta B chain antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 369-397 from the human protein was used as the immunogen for the Inhibin beta B chain antibody.
Limitation:
This Inhibin beta B chain antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse
Uniprot #:
P09529