NSJ Bioreagents

TAB3 Antibody

Product Code:
 
NSJ-N1201
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the TAB3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of human samples with TAB3 antibody at 4ug/ml.
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Western blot testing of human samples with TAB3 antibody at 4ug/ml.

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CodeSizePrice
NSJ-N1201-25UG25 ug£254.00
Quantity:
NSJ-N1201-100UG100 ug£450.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 4-8ug/ml
Application Note:
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
TAB3, a TAB2-like protein, is a mediator of TAK1 activation in IL-1 and TNF signaling. IL-1 and TNF are cytokines involved in the inflammation process, initiating signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (MAPKs). TAB3 functions as an adapter, linking TAK1 and TRAF6 or TRAF2. This kinase complex phosphorylates IkB, which keeps NF-kB inactive and sequestered in the cytoplasm. Phosphorylation leads to IkB degradation, activating NF-kB, which translocates to the nucleus, binds to DNA response elements and can begin multiple signaling cascades.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
257397
Immunogen:
A recombinant protein fragment from the N-terminal region of human TAB3 was used as the immunogen for this antibody.
Limitation:
This TAB3 antibody is available for research use only.
Purity:
Protein A purified antibody
Species Reactivity :
Human, Mouse