NSJ Bioreagents

OTUD5 Antibody / DUBA

Product Code:
 
NSJ-N1110
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of human samples with OTUD5 antibody at 2ug/ml.~
2 / 2
Western blot testing of mouse samples with OTUD5 antibody at 4ug/ml.
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Western blot testing of human samples with OTUD5 antibody at 2ug/ml.~
Western blot testing of mouse samples with OTUD5 antibody at 4ug/ml.

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CodeSizePrice
NSJ-N1110-25UG25 ug£254.00
Quantity:
NSJ-N1110-100UG100 ug£450.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 2-5ug/ml
Application Note:
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
OTUD5 (ovarian tumor domain-containing 5), also called DUBA (Deubiquitinating enzyme A), is a product of the OTUD5 gene, and a suppressor of the innate immune response via its deubiquitinating activity. The Innate immune systems provide immediate but short-lived defense against infection identified by PRRs, or pattern recognition receptors. OTUD5 cleaves the lysine-63-linked polyubiquitin chains of TRAF3, causing it to dissociate from TBK1, thereby failing to stimulate IFN type 1 production and leading to a suppressed innate immune response.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
55593
Immunogen:
A recombinant protein fragment from the C-terminal region of human OTUD5 was used as the immunogen for this antibody.
Limitation:
This OTUD5 antibody is available for research use only.
Purity:
Protein A affinity chromatography
Species Reactivity :
Human, Mouse, Rat