NSJ Bioreagents

ICAD Antibody

Product Code:
 
NSJ-N1102
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
1 / 1
Western blot test of mouse samples with ICAD antibody at 4ug/ml.
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Western blot test of mouse samples with ICAD antibody at 4ug/ml.

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CodeSizePrice
NSJ-N1102-25UG25 ug£254.00
Quantity:
NSJ-N1102-100UG100 ug£450.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 4-8ug/ml
Application Note:
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
During apoptosis, toxic or useless cells are broken down for removal. DFF, or DNA fragmentation factor, is a heterodimeric protein which mediates DNA fragmentation and chromatin condensation during apoptosis. DFFB is the active DFF subunit but remains inactive while bound to DFFA, also call ICAD (Inhibitor of caspase-activated DNase). Caspase-3 cleaves ICAD, which then disassociates from DFFB. The disassociation removes the inhibitory effects of ICAD, activating DFFB and beginning the DNA fragmentation process.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
1676
Immunogen:
A recombinant protein fragment from human ICAD was used as the immunogen for this antibody.
Limitation:
This ICAD antibody is available for research use only.
Purity:
Protein A affinity chromatography
Species Reactivity :
Mouse