NSJ Bioreagents

Clusterin Antibody / Apolipoprotein J / APO-J

Product Code:
 
NSJ-V9387
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
CLU/4733
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot the APO-J antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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SDS-PAGE analysis of purified, BSA-free APO-J antibody (clone CLU/4733) as confirmation of integrity and purity.
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SDS-PAGE analysis of purified, BSA-free APO-J antibody (clone CLU/4733) as confirmation of integrity and purity.

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CodeSizePrice
NSJ-V9387-20UG20ug£264.00
Quantity:
NSJ-V9387-100UG100ug£534.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the APO-J antibody should be determined by the researcher.
Description:
Clusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP40 and testosterone-repressed prostate message 2 (TRPM2), is a secretory, heterodimeric glycoprotein that influences immune regulation, cell adhesion, transformation, lipid transportation, tissue remodeling, membrane recycling and cell-cell interactions. Clusterin is synthesized as a 449 amino acid polypeptide that is post-translationally cleaved at an internal bond between Arg 227 and Ser 228. The beta subunit corresponds to residues 23-227. The alpha subunit corresponds to residues 228-449. Overexpression of Clusterin appears to be more common in late stages of mammary tumor progression. Clusterin markedly influences Amyloid structure and neuritic toxicity in vivo and may influence Alzheimer s pathogenesis.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A portion of amino acids 185-287 was used as the immunogen for the APO-J antibody.
Limitation:
This APO-J antibody is available for research use only.
Localization:
Nucleus, Cytoplasm
Purity:
Protein A/G affinity
Species Reactivity :
Human
Uniprot #:
P10909