TargetMol

Ergolide

Product Code:
 
TAR-T13686
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13686-1mg1mg£164.00
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TAR-T13686-5mg5mg£270.00
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TAR-T13686-1mL1 mL * 10 mM (in DMSO)£309.00
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TAR-T13686-10mg10mg£412.00
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TAR-T13686-25mg25mg£627.00
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TAR-T13686-50mg50mg£843.00
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Quantity:
TAR-T13686-100mg100mg£1,107.00
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  • Further Information
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Further Information

Bioactivity:
Ergolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB. Ergolide is a sesquiterpene lactone isolated from the dried flowers of Inula Britannica.
CAS:
54999-07-4
Formula:
C17H22O5
Molecular Weight:
306.358
Pathway:
NF-κb
Purity:
0.9956
SMILES:
[H][C@]12C[C@@H](C)[C@]3([H])CCC(=O)[C@@]3(C)[C@@H](OC(C)=O)[C@]1([H])C(=C)C(=O)O2
Target:
NF-κB

References

1. Whan Han J, et al. Ergolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-kappaB. Br J Pharmacol. 2001 Jun;133(4):503-12.