TargetMol

Kaempferitrin

Product Code:
 
TAR-T3386
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3386-1mg1mg£105.00
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TAR-T3386-5mg5mg£171.00
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TAR-T3386-1mL1 mL * 10 mM (in DMSO)£197.00
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TAR-T3386-10mg10mg£245.00
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TAR-T3386-25mg25mg£365.00
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TAR-T3386-50mg50mg£507.00
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TAR-T3386-100mg100mg£691.00
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TAR-T3386-500mg500mg£1,324.00
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Further Information

Bioactivity:
Kaempferitrin has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucose-metabolizing enzymes, promotes glucose homeostasis. Kaempferitrin exerts immunostimulatory effects on immune responses mediated by splenocytes, macrophages, PBMC and NK cells. Kaempferitrin induces cytotoxic effects to include: cell cycle arrest in G1 phase and apoptosis via the intrinsic pathway in a caspase-dependent pathway.
CAS:
482-38-2
Formula:
C27H30O14
Molecular Weight:
578.523
Pathway:
Metabolism; Tyrosine Kinase/Adaptors; Cell Cycle/Checkpoint
Purity:
0.9951
SMILES:
C[C@@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(-c2ccc(O)cc2)c(O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)c3=O)[C@H](O)[C@H](O)[C@H]1O
Target:
cell cycle arrest; Glucokinase; IGF-1R

References

Da Silva D, et al. IUBMB Life. 2014 May;66(5):361-70. Del Carmen Ju?rez-V?zquez M, et al. J Ethnopharmacol. 2013 Jun 21;148(1):337-40. Cazarolli LH, et al. Eur J Pharmacol. 2013 Jul 15;712(1-3):1-7.