TargetMol

14-Deoxyandrographolide

Product Code:
 
TAR-T8288
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8288-1mg1mg£130.00
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TAR-T8288-5mg5mg£213.00
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TAR-T8288-1mL1 mL * 10 mM (in DMSO)£227.00
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TAR-T8288-10mg10mg£303.00
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TAR-T8288-25mg25mg£463.00
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TAR-T8288-50mg50mg£621.00
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Further Information

Bioactivity:
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.
CAS:
4176-97-0
Formula:
C20H30O4
Molecular Weight:
334.456
Pathway:
Apoptosis;
Purity:
0.9989
SMILES:
C[C@@]1(CO)C(O)CC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12
Target:
Apoptosis;

References

Roy DN, et al. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Br J Pharmacol. 2010 Aug;160(7):1823-43.