TargetMol

Ganoderic acid C2

Product Code:
 
TAR-TN1661
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1661-50mg50mgEnquire
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TAR-TN1661-1mg1mg£115.00
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TAR-TN1661-5mg5mg£185.00
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TAR-TN1661-1mL1 mL * 10 mM (in DMSO)£221.00
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TAR-TN1661-10mg10mg£254.00
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Further Information

Bioactivity:
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (IC50 = 3.8 ?M).
CAS:
103773-62-2
Formula:
C30H46O7
Molecular Weight:
518.691
Pathway:
Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Neuroscience; GPCR/G Protein
Purity:
0.98
SMILES:
[H][C@@]12C[C@H](O)C3=C(C(=O)C[C@]4(C)[C@H](C[C@H](O)[C@@]34C)[C@H](C)CC(=O)C[C@@H](C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
Target:
Reductase; Histamine Receptor; Immunology/Inflammation related

References

Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76(15):1691-3. Guo XY, et al. Structural characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73.