TargetMol

Allocryptopine

Product Code:
 
TAR-TN3379
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Allocryptopine has certain effects on anti-injury for hepatocyte, ameliorating liver function, and prohibiting hepatic fibrosis; it increases mRNA levels of cytochromes P450 1A in human hepatocytes and HepG2 cells independently of AhR. Allocryptopine induces a relaxing effect on the ileum by inhibiting phosphodiesterase enzyme, and thus elevating cellular cAMP and its contractile effect on the urinary bladder by affecting alpha-adrenergic receptors in this tissue, it can block human ether-a-go-go related gene (hERG) potassium channels expressed in HEK293 cells.
CAS:
24240-04-8
Formula:
C21H23NO5
Molecular Weight:
369.417
Pathway:
Membrane transporter/Ion channel; GPCR/G Protein; Metabolism
Purity:
0.98
SMILES:
COc1ccc2CC(=O)c3cc4OCOc4cc3CCN(C)Cc2c1OC
Target:
cAMP; P45; Potassium Channel