TargetMol

Broussonin A

Product Code:
 
TAR-TN3539
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN3539-5mg5mg£488.00
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Quantity:
TAR-TN3539-1mL1 mL * 10 mM (in DMSO)£496.00
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This product comes from: United States.
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Further Information

Bioactivity:
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-luciferase reporter genes. Broussonin A can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay; it suppresses lipopolysaccharide (LPS)-stimulated inducible nitric oxide synthase (iNOS) expression at the transcriptional level through modulating NF-κB and down-regulation of the Akt and ERK signaling pathways.
CAS:
73731-87-0
Formula:
C16H18O3
Molecular Weight:
258.32
Pathway:
Immunology/Inflammation; Cytoskeletal Signaling; MAPK; NF-κb; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
COc1ccc(CCCc2ccc(O)cc2)c(O)c1
Target:
ERK; IL Receptor; IκB/IKK; NOS; NF-κB; Akt