TargetMol

5 α-Pregnane-3β,6 α-diol-20-one

Product Code:
 
TAR-T13518
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13518-1mg1mg£115.00
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TAR-T13518-2mg2mg£132.00
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TAR-T13518-5mg5mg£168.00
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TAR-T13518-1mL1 mL * 10 mM (in DMSO)£177.00
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TAR-T13518-10mg10mg£242.00
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TAR-T13518-25mg25mg£375.00
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Quantity:
TAR-T13518-50mg50mg£528.00
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TAR-T13518-100mg100mg£727.00
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Quantity:
TAR-T13518-500mg500mg£1,420.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite of progesterone. It can be produced in starved androgen-responsive prostate cancer cells.
CAS:
21853-11-2
Formula:
C21H34O3
Molecular Weight:
334.5
Purity:
0.998
SMILES:
[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C[C@H](O)[C@@]2([H])C[C@@H](O)CC[C@]12C

References

1. Zhang J, et al. Progesterone metabolism in human fibroblasts is independent of P-glycoprotein levels and Niemann-Pick type C disease. J Steroid Biochem Mol Biol. 1999 Sep-Oct;70(4-6):123-31. 2. de Mello Martins AGG, et al. CYP17A1-independent production of the neurosteroid-derived 5?-pregnan-3?,6?-diol-20-one in androgen-responsive prostate cancer cell lines under serum starvation and inhibition by Abiraterone. J Steroid Biochem Mol Biol. 2017 Nov;174:183-191.