TargetMol

Tacrine

Product Code:
 
TAR-T21439
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T21439-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T21439-5mg5mg£124.00
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TAR-T21439-10mg10mg£148.00
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TAR-T21439-25mg25mg£200.00
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TAR-T21439-50mg50mg£257.00
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TAR-T21439-100mg100mg£371.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
Tacrine is an indirect cholinergic agonist and centrally acting anticholinesterase. It is approved for the treatment of Alzheimer's disease.
CAS:
321-64-2
Formula:
C13H14N2
Molecular Weight:
198.269
Pathway:
Neuroscience
Purity:
0.9994
SMILES:
Nc1c2CCCCc2nc2ccccc12
Target:
AChR

Documents

References

1. Ismaili L, Refouvelet B, Benchekroun M, Brogi S, Brindisi M, Gemma S, Campiani G, Filipic S, Agbaba D, Esteban G, Unzeta M, Nikolic K, Butini S, Marco-Contelles J. Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease. Prog Neurobiol. 2016 Jan 18. pii: S0301-0082(15)00162-8. doi: 10.1016/j.pneurobio.2015.12.003. [Epub ahead of print] Review. 2. Minarini A, Milelli A, Simoni E, Rosini M, Bolognesi ML, Marchetti C, Tumiatti V. Multifunctional tacrine derivatives in Alzheimer's disease. Curr Top Med Chem. 2013;13(15):1771-86. Review. PubMed PMID: 23931443. 3. Romero A, Cacabelos R, Oset-Gasque MJ, Samadi A, Marco-Contelles J. Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer's disease. Bioorg Med Chem Lett. 2013 Apr 1;23(7):1916-22. doi: 10.1016/j.bmcl.2013.02.017. Epub 2013 Feb 16. Review. PubMed PMID: 23481643. 4. Kor?be?n? J, Spilovsk? K, Benek O, Mus?lek K, Soukup O, Ku?a K. [Tacrine and its derivatives in the therapy of Alzheimers disease]. Ceska Slov Farm. 2012 Oct;61(5):210-21. Review. Czech. PubMed PMID: 23256654.