TargetMol

Armepavine

Product Code:
 
TAR-T3775
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3775-5mg5mg£295.00
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Further Information

Bioactivity:
Armepavine exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition of NF-κB, JunD and C/EBP pathways. It improves experimental autoimmune crescentic glomerulonephritis.
CAS:
524-20-9
Formula:
C19H23NO3
Molecular Weight:
313.397
Pathway:
NF-κb
Purity:
0.95
SMILES:
COc1cc2CCN(C)[C@H](Cc3ccc(O)cc3)c2cc1OC
Target:
IκB/IKK; NF-κB

References

Ka SM, et al. (S)-armepavine from Chinese medicine improves experimental autoimmune crescentic glomerulonephritis. Rheumatology (Oxford). 2010 Oct;49(10):1840-51. Weng TC, et al. Effects of armepavine against hepatic fibrosis induced by thioacetamide in rats. Phytother Res. 2012 Mar;26(3):344-53.