TargetMol

(+)-Kavain

Product Code:
 
TAR-T4590
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4590-5mg5mg£104.00
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Quantity:
TAR-T4590-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T4590-10mg10mg£117.00
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TAR-T4590-25mg25mg£145.00
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Quantity:
TAR-T4590-50mg50mg£180.00
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Further Information

Bioactivity:
Kawain is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
CAS:
500-64-1
Formula:
C14H14O3
Molecular Weight:
230.263
Pathway:
Membrane transporter/Ion channel; Metabolism; Neuroscience
Purity:
0.98
SMILES:
COC1=CC(=O)O[C@H](C1)C=Cc1ccccc1
Target:
Calcium Channel; GABA Receptor; Sodium Channel; Monoamine Transporter

References

Ma Y, et al. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. Drug Metab Dispos. 2004 Nov;32(11):1317-24. Uebelhack R, et al. Inhibition of platelet MAO-B by kava pyrone-enriched extract from Piper methysticum Forster (kava-kava). Pharmacopsychiatry. 1998 Sep;31(5):187-92. Baum SS, et al. Effect of kava extract and individual kavapyrones on neurotransmitter levels in the nucleus accumbens of rats. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Oct;22(7):1105-20.