TargetMol

Geranylgeraniol

Product Code:
 
TAR-TN6714
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN6714-100mg100mg£103.00
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TAR-TN6714-200mg200mg£118.00
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TAR-TN6714-500mg500mg£145.00
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This product comes from: United States.
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Further Information

Bioactivity:
Geranylgeraniol is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol protects monocytes against statin-induced cytotoxicity and suppresses the growth of Mycobacterium.
CAS:
24034-73-9
Formula:
C20H34O
Molecular Weight:
290.491
Pathway:
Apoptosis
Purity:
0.98
SMILES:
CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCO
Target:
Apoptosis

References

Schumacher MM, et al. The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase. Elife. 2015 Mar 5;4. Pabst AM, et al. Isoprenoid geranylgeraniol: the influence on cell characteristics of endothelial progenitor cells after bisphosphonate therapy in vitro. Clin Oral Investig. 2015 Sep;19(7):1625-33. Zafar S, et al. Zoledronic acid and geranylgeraniol regulate cellular behaviour and angiogenic gene expression in human gingival fibroblasts. J Oral Pathol Med. 2014 Oct;43(9):711-21. Fernandes NV, et al. Geranylgeraniol suppresses the viability of human DU145 prostate carcinoma cells and the level of HMG CoA reductase. Exp Biol Med (Maywood). 2013 Nov 1;238(11):1265-74.