Leinco Technologies

Anti-Mouse IL-1 R1, Type 1-Biotin

Product Code:
 
LEI-I-434
Product Group:
 
Primary Antibodies
Host Type:
 
Hamster
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
JAMA-147
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Shipping:
 
Ambient
Storage:
 
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
 

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CodeSizePrice
LEI-I-434-50ug50 ug£156.00
Quantity:
LEI-I-434-500ug500 ug£298.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Biotin
Format:
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Long Description:
IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1α and IL-1β exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1α and IL-1β, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
Target:
Interleukin-1 R1