Leinco Technologies

Anti-Human Tetratricopeptide Repeat Protein 5 (TTC5)

Product Code:
 
LEI-T295
Product Group:
 
Primary Antibodies
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
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CodeSizePrice
LEI-T295-20ug20 ug£199.00
Quantity:
LEI-T295-0.1mg0.1 mg£591.00
Quantity:
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Further Information

Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Formulation:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Immunogen:
PN:T302
Long Description:
Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats.1 Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90,2 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5,3 suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
Target:
Tetratricopeptide Repeat Protein 5

References

1. Blatch, GL. et al. (1999) BioEssays 21:932 2. Song, Y. et al. (2005) J. Biol. Chem. 280:34178 3. Yang, J. et al. (2005) EMBO J. 24:1