Leinco Technologies

Anti-Mouse/Human IL-5 - Purified in vivo GOLD™ Functional Grade

Product Code:
 
LEI-I-1060
Product Group:
 
Primary Antibodies
Host Type:
 
Rat
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
TRFK5
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Depletion
  • ELISpot
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Functional Study
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • In Vivo Assay
  • Mass Cytometry (CyTOF)
  • Neutralisation
  • Western Blot (WB)
Shipping:
 
2-8°C
Storage:
 
This Low Endotoxin Functional Formulation GOLD Antibody is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-I-1060-1.0mg1.0 mg£244.00
Quantity:
LEI-I-1060-5mg5 mg£716.00
Quantity:
LEI-I-1060-25mg25 mg£1,780.00
Quantity:
LEI-I-1060-50mg50 mg£2,844.00
Quantity:
LEI-I-1060-100mg100 mg£3,971.00
Quantity:
Prices exclude any Taxes / VAT
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Antigen Distribution:
Mast cells, T cells, eosinophils
Concentration:
? 2.0 mg/ml
Conjugate/Tag/Label:
in vivo GOLD™
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
Partially-purified T cell clone supernatant
Long Description:
IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma.
NCBI Gene:
161913567
Purity:
?95% monomer by analytical SEC, >95% by SDS Page
Target:
IL-5