Leinco Technologies

Anti-MPXV B6R (Clone: MPXV-13)

Product Code:
 
LEI-LT555
Product Group:
 
Primary Antibodies
Host Type:
 
Virus
Antibody Isotype:
 
Human IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MPXV-13
Regulatory Status:
 
RUO
Target Species:
  • Monkeypox virus
  • Virus
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Neutralisation
Shipping:
 
Blue Ice
Storage:
 
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage aseptically aliquot in working volumes without diluting and store at ? -70°C. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-LT555-250ug250 ug£231.00
Quantity:
LEI-LT555-1.0mg1.0 mg£410.00
Quantity:
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This product comes from: US.
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Further Information

Antigen Distribution:
B5 is a surface antigen on the enveloped virion.
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
Sequenced from PBMCs from a donor who had recovered from a naturally-occurring MPXV infection
Long Description:
Monkeypox virus (MPXV) is a zoonotic member of the Orthopoxvirus genus in the Poxviridae family1. It is the next most pathogenic poxvirus after smallpox. Two genetic clades, West African and Central African (Congo Basin), have been characterized; the latter is capable of human-to-human transmission1,2. Monkeypox has gained clinical relevance due to the eradication of smallpox, which has created opportunities for increased prevalence and viral mutations that may affect virulence1, 2. Rodents are thought to be the natural reservoir, with transmission through contact with bodily fluids and feces. Case fatality rates are
Purity:
?95% monomer by analytical SEC
Target:
Monkeypox

References

1. Sklenovsk? N, Van Ranst M. Front Public Health. 6:241. 2018. 2. Moore M, Zahra F. 2021 Oct 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan?. 3. McConnell S, Herman YF, Mattson DE, et al. Am J Vet Res. 25:192-195. 1964. 4. Hammarlund E, Lewis MW, Carter SV, et al. Nat Med. 11(9):1005-1011. 2005. 5. Gilchuk I, Gilchuk P, Sapparapu G, et al. Cell. 167(3):684-694.e9. 2016. 6. Moss B. Immunol Rev.239:8?26. 2011.