MBL

Anti-TCR beta (Mouse) mAb-PerCP-Cy5.5

Product Code:
 
MBL-FP20887002
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Hamster
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
H57-597
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP2088700225 ug£243.00
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Further Information

Background:
The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR). The crosslinking induces activation and proliferation of T cells, as a plate-bound or a soluble H57-597, or the plate-bound antibody can induce apoptosis, based on assay conditions. The beta chain of the TCR can combine with the alpha chain of the receptor to produce the alpha-beta TCR, which is expressed by the NKT cells, by the NK1.1+ thymocytes and most of the T cells. The beta chain does not react with the gamma-delta TCR-bearing cells, expressed by a small number of T cells. This antibody can be used as a phenotypic marker for the TCR beta expressing cells or for the functional purpose of TCR-mediated cell activation or apoptosis.
Concentration:
0.2 mg/mL
Conjugate:
PerCP-Cy5.5
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
TCR beta

Documents

References

Sanchez-Madrid, F., et al., J Exp Med. 158, 586-602 (1983) Ault, K. A., & Springer, T. A., J Immunol. 126, 359-364 (1981) Springer, T., et al., Eur J Immunol. 8, 539-551 (1978)