PE/Cyanine5.5 Anti-Mouse CD107a Antibody[1D4B]

CD107a/LAMP-1

The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+T cells, as well as, some malignant tumor cells.

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

5 uL/Test

PE/Cyanine5.5

16783

LAMP-1;Lysosome-associated membrane glycoprotein 1; lysosomal membrane glycoprotein 1; CD107 antigen-like family member A; lysosome-associated membrane protein 1;

P11438

Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.