Elabscience

Recombinant PCBP2 Monoclonal Antibody

Product Code:
 
E-AB-81594
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
R01-2F5
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot detection of PCBP2/hnRNP E2 in C6,3T3 cell lysates using PCBP2/hnRNP E2 Rabbit mAb(1:1000 diluted).Predicted band size:39kDa.Observed band size: 35-45kDa.

Western blot detection of PCBP2/hnRNP E2 in C6,3T3 cell lysates using PCBP2/hnRNP E2 Rabbit mAb(1:1000 diluted).Predicted band size:39kDa.Observed band size: 35-45kDa.

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E-AB-81594-50uL50uL£184.00
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E-AB-81594-100uL100uL£251.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
PCBP2
Background:
The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
39kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
A synthetic peptide of human PCBP2
ObservedMW:
35/45kDa
Purification method:
Affinity Purified
Target Synonym:
PCBP2;HNRNPE2;HNRPE2;hnRNP-E2
UNIProt ID:
Q15366

Documents