Recombinant LC3A Monoclonal Antibody

LC3A

LC3,also known as microtubule-associated protein 1 light chain 3 (MAP1LC3),is a mammalian homolog of the yeast Atg8p (autophagy-related 8 protein) that is involved in autophagy process. Three isoforms of LC3 exist as LC3A,LC3B,and LC3C. LC3 is first synthesized as pro-LC3,and undergoes C-terminal cleavage to yield a cytosolic precursor known as LC3-I. During autophagy LC3-I is subsequently conjugated to PE lipid as lipidated form: LC3-II. The lipidated form migrates faster on SDS-PAGE gel. The increased the level of LC3-II has been widely used as autophagy marker. This antibody recognizes both LC3-I and LC3-II.

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

14kDa

300 ug/mL

Unconjugated

WB 1:500-1:1000

A synthetic peptide of human MAP1LC3A

16kDa

Affinity Purified

ATG8E;Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;LC3;LC3A;MAP1 light chain 3 like protein 1;MAP1 light chain 3-like protein 1;MAP1A/1B light chain 3 A;MAP1A/MAP1B LC3 A;MAP1A/MAP1B light chain 3 A;MAP1ALC3;MAP1BLC3;Map1lc3a;Microtubule associated proteins 1A/1B light chain 3;Microtubule-associated protein 1 light chain 3 alpha;Microtubule-associated proteins 1A and 1B;light chain 3;Microtubule-associated proteins 1A/1B light chain 3A;MLP3A

Q9H492