Elabscience

Recombinant IMPDH2 Monoclonal Antibody

Product Code:
 
E-AB-81572
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
R06-1B8
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 2
Western blot detection of IMPDH2 in Hela,A549,HL-60,U2OS,C6 using IMPDH2 Rabbit mAb(1:1000 diluted)
2 / 2
Immunohistochemistry of IMPDH2 in paraffin-embedded Human breast cancer tissue using IMPDH2 Rabbit mAb at dilution 1:50
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Western blot detection of IMPDH2 in Hela,A549,HL-60,U2OS,C6 using IMPDH2 Rabbit mAb(1:1000 diluted)
Immunohistochemistry of IMPDH2 in paraffin-embedded Human breast cancer tissue using IMPDH2 Rabbit mAb at dilution 1:50

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CodeSizePrice
E-AB-81572-50uL50uL£184.00
Quantity:
E-AB-81572-100uL100uL£251.00
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Further Information

Abbreviation:
IMPDH2
Background:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
56kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000 IHC 1:50-1:100
Immunogen:
A synthetic peptide of human IMPDH2
ObservedMW:
56kDa
Purification method:
Affinity Purified
Target Synonym:
IMDH2;IMP (inosine monophosphate) dehydrogenase 2;IMP dehydrogenase 2;IMP oxireductase 2;IMPD 2;IMPD2;IMPDH 2;IMPDH II;IMPDH-II;Impdh2;Inosine 5' monophosphate dehydrogenase 2;Inosine 5' phosphate dehydrogenase 2;Inosine monophosphate dehydrogenase type II;Inosine-5''-monophosphate dehydrogenase 2
UNIProt ID:
P12268

Documents