Elabscience

Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody

Product Code:
 
E-AB-81528
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
R07-1I6
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot detection of Angiotensin II Type 1 Receptor in HepG2 cell lysates using Angiotensin II Type 1 Receptor Rabbit mAb(1:1000 diluted).Predicted band size:41kDa.Observed band size:41kDa.
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Western blot detection of Angiotensin II Type 1 Receptor in HepG2 cell lysates using Angiotensin II Type 1 Receptor Rabbit mAb(1:1000 diluted).Predicted band size:41kDa.Observed band size:41kDa.

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E-AB-81528-50uL50uL£184.00
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E-AB-81528-100uL100uL£251.00
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Further Information

Abbreviation:
Angiotensin II Type 1 Receptor
Background:
Angiotensin II (Ang II),the main effector molecule of the renin-angiotensin system,exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1,also named as AT1R),thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone,cardiovascular function,salt and water homeostasis,AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease,from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
41kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
A synthetic peptide of human Angiotensin II Type 1 Receptor
ObservedMW:
41kDa
Purification method:
Affinity Purified
Target Synonym:
AGTR1;AG2S;AGTR1B;AT1;AT1AR;AT1B;AT1BR;AT1R;AT2R1;HAT1R
UNIProt ID:
P30556

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